Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 1 (2004)
Original Article
1. Over-expression of Wilm’s Tumor Gene 1 (WT1) in Iranian Patients with Acute Myeloblastic Leukemia

Hossein Asgarian; Mahdi Shabani; Parvaneh Vosoogh; Ramazan Ali Sharifian; Soheila Gharagozlou; Jalal Khoshnoodi; Tahereh Shahrestani; Mahin Kordmahin; Abdolfattah Sarrafnejad; Mahmood Jeddi Tehrani; Hodjatallah Rabbani; Fazel Shokri

Volume 2, Issue 4 , Autumn 2005, Pages 182-190

  Background: The Wilm’s tumor gene 1 (WT1) encodes a zinc finger transcription factor that is inactivated in a subset of Wilm’s tumors. It plays a crucial role in growth, proliferation and development of some embryonic and adult organs. WT1 is expressed as a tumor associated antigen (TAA) ...  Read More

Original Article
2. Serum Level of HER-2 Extracellular Domain in Iranian Patients with Breast Cancer: A Follow-up Study

Mehrnoosh Doroudchi; Abdolrasoul Talei; Helmout Modjtahedi; Alamtaj Samsami Dehaghani; Abdol Mohammad Pezeshki; Hilary Thomas; Abbas Ghaderi

Volume 2, Issue 4 , Autumn 2005, Pages 191-200

  Background: A soluble form of HER-2/neu extracellular domain (sHER-2) is reported to be released in the sera of metastatic breast cancer patients. Objective: To measure the level of sHER-2 in sera of 115 breast cancer patients. Methods: Serial samples of 27 patients with metastasis, 18 non-metastatic ...  Read More

Original Article
3. Deficient Expression of Bruton's Tyrosine Kinase in Monocytes from X-Linked Agammaglobulinemia as Evaluated by a Flow Cytometric Analysis and its Clinical Application to Carrier Detection

Asghar Aghamohammadi; Ali Akbar Amirzargar; Nima Parvaneh; Paul Marjousef; Mostafa Moin; Abdolhassan Farhoudi; Mehdi Yeganeh; Toshio Miyawaki

Volume 2, Issue 4 , Autumn 2005, Pages 201-207

  Background: The B-cell defect in X-linked agammaglobulinemia (XLA) is caused by mutations in the gene for Bruton's tyrosine kinase (BTK). BTK mutations result in deficient expression of BTK protein in peripheral blood monocytes. Methods: Using the anti-BTK monoclonal antibody (48-2H), a flow cytometric ...  Read More

Original Article
4. Effects of Recombinant Human Erythropoietin Pretreatment on Anti-HLA Antibody Titer: A Preclinical Experience in Rats

Akbar Vahdati; Minoo Adib; Shirin Kashfi; Taji Afrooz; Edna Abkar

Volume 2, Issue 4 , Autumn 2005, Pages 208-212

  Background: Erythropoietin (EPO) was first known as a factor for red blood cell proliferation and differentiation. New studies show the effects of EPO on immune system. Objective: In this study, the effects of pretreatment with recombinant human erythropoietin (rHuEPO) on the anti-human leukocyte antibody ...  Read More

Original Article
5. The Assessment of NK Cytotoxicity and CD56+/CD16+ Phenotype by Flowcytometry in PBL Isolated from Women with Recurrent Spontaneous Abortion

Alireza Andalib; Abbas Rezaie; Farzad Oreizy; Sima Baluchi

Volume 2, Issue 4 , Autumn 2005, Pages 213-219

  Background: Human peripheral blood NK cells constitutively express CD56 and CD16 antigens. Peripheral blood NK cells seem to be strongly related with decidual NK cells, and may reflect the decidual NK cell functional status. There are varied reports concerning the relationship between NK cell cytotoxicity ...  Read More

Original Article
6. Evaluation of the Serum Levels of Immunoglobulin and Complement Factors in b-thalassemia Major Patients in Southern Iran

Ahmad Amin; Susan Jalali; Reza Amin; Soheila Aale-yasin; Nima Jamalian; Mehran Karimi

Volume 2, Issue 4 , Autumn 2005, Pages 220-225

  Background: Beta-thalassemia major is one of the major health problems in our country. Many studies have confirmed the fact that, these patients have an increased susceptibility to bacterial infections. Objective: In this study, we have assessed the humoral immune system in 68 thalassemic patients by ...  Read More

Original Article
7. Polymorphism in the First Intron of Interferon-Gamma Gene (+874T→A) in Iranian Patients with Brucellosis

Manoochehr Rasouli; Simin Kiany; Abdolvahhab Alborzi

Volume 2, Issue 4 , Autumn 2005, Pages 226-231

  Background: Brucella is a gram-negative bacterium, causing acute and chronic infection in humans and animals. Cell-mediated immunity is the main protective immune response against Brucella spp. Activation of macrophages by IFN-γ and generation of reactive oxygen intermediates and nitric oxide are ...  Read More

Original Article
8. Ethics of Tissue and Stem Cell Transplantation

Behrouz Nikbin; Mandana Mohyeddin Bonab; Fatemeh Talebian

Volume 2, Issue 4 , Autumn 2005, Pages 232-240

  Tissue and cell transplantation are regarded as a popular procedure in clinical sciences, prospecting a new horizon for several incurable diseases. Along with its usefulness, many ethical concerns accompany this development. The ethical issue of organ transplant is unique to the source used which includes: ...  Read More