Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 1 (2004)
Original Article
1. Production and Characterization of Murine Monoclonal Antibodies Recognizing Conformational and Linear Epitopes Localized on Human IgA2 Molecules

Fatemeh Hajighasemi; Soheila Gharagozlou; Nasrin Moheghi; Roya Ghods; Jalal Khoshnoodi; Fazel Shokri

Volume 2, Issue 3 , Summer 2005, Pages 125-133

  Background: There are two subclasses of human IgA (IgA1 and IgA2) that differ in antigenic properties and in chemical composition. The constant domains of α1 and α2 heavy chains have >95% sequence homology though major structural differences exist in the hinge region. Quantitation of IgA ...  Read More

Original Article
2. Construction of a Eukaryotic Plasmid Encoding Bacillus anthracis Protective Antigen, a Candidate for DNA Vaccine

Fatemeh Vahedi; Naser Taiebi Meibody; Mahdi KianiZadeh; Mahmoud Mahmoudi

Volume 2, Issue 3 , Summer 2005, Pages 134-140

  Background: DNA immunization with plasmid DNA encoding bacterial, viral, parasitic and tumor antigens has been reported to trigger protective immunity. Objective: To evaluate the use of a DNA immunization strategy for protection against anthrax, a plasmid was constructed. Methods: The partialsequence ...  Read More

Original Article
3. Glutathione S-transferases Null Genotype in Acute Myeloid Leukaemia

Mohammad Hasan Sheikhha; Mehdi Kalantar; Khalid Tobai; John A. Liu Yin

Volume 2, Issue 3 , Summer 2005, Pages 141-151

  Background: The glutathione S-transferase (GST) family of metabolising enzymes plays an important role in the detoxification of mutagens and carcinogens. The expression of many of these cancer susceptibility enzymes is genetically polymorphic. An increased frequency of GST-null genotypes has been associated ...  Read More

Original Article
4. Investigation of NK Cell Population in Peripheral Blood and Tumor Lesions of Patients with Breast Cancer

Sousan Farazmand; Dawar Amani; Zohair-Mohammad Hassan

Volume 2, Issue 3 , Summer 2005, Pages 152-157

  Background: Alteration in peripheral blood lymphocytes (PBLs) is usually investigated to provide an evidence of the host immune responses to tumor antigens. The tumor infiltrating NK cells interact most closely with the tumor cells and more accurately reflect tumor host interactions. Objective: To analyze ...  Read More

Original Article
5. Interleukin-10 Promoter Polymorphisms and Breast Cancer Risk in Iranian Women

Hossein Abdolrahim-Zadeh; Niloufar Hakkakian; Reza Asadollahi; Behrouz Gharesifard; Jamal Sarvari; Eskandar Kamali-Sarvestani; Abdolrasoul Talei

Volume 2, Issue 3 , Summer 2005, Pages 158-165

  Background: IL-10 is an anti-inflammatory cytokine which is involved in tumorigenesis. Over production of IL-10 and elevated number of IL-10 generating mononuclear cells in breast tumor tissue has already been shown. Objective: To determine the association of IL-10 promoter polymorphisms with increased ...  Read More

Original Article
6. Study of Chenopodium Album Allergenic Extract to Induce Allergic Asthma in Murine Model

Tahereh Mousavi; Nahid Asadi; Majid Tebyanian

Volume 2, Issue 3 , Summer 2005, Pages 166-171

  Background: The incidence of allergic and asthmatic diseases has been continuously increased in both industrial and developing countries. Extracts from various known allergens are used for the diagnostic and therapeutic purposes. Objective: To investigate the effects of an extract prepared from Chenopodium ...  Read More

Original Article
7. Detection of HBV DNA in HBsAg Negative Normal Blood Donors

Abbasali Pourazar; Mansoor Salehi; Aabollah Jafarzadeh; Mohammad Kazemi Arababadi; Farzad Oreizi; Keivan Shariatinezhad

Volume 2, Issue 3 , Summer 2005, Pages 172-176

  Background: The risk of infection by transfusion-transmitted viruses has been reduced remarkably. However, a zero-risk blood supply is still desirable. The screening for antibody to HBc (anti-HBc) has been shown as an alternative test for the detection of HBV infection. Objective: The main aim of this ...  Read More

Original Article
8. Seroprevalence of Toxoplasmosis in High School Girls in Fasa District, Iran

Gholamreza Hatam; Azra Shamseddin; Farhoud Nikouee

Volume 2, Issue 3 , Summer 2005, Pages 177-181

  Background: Toxoplasmosis is a parasitic disease caused by protozoan, Toxoplasma gondii. Infections of human are common and are usually asymptomatic. The infection may be serious if is transmitted to the fetus during pregnancy. Prophylactic measures, early detection of the infection and treatment can ...  Read More