Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. Association between HLA-DQB1*03:01 and Bullous Pemphigoid in Iranian Patients

Nafiseh Esmaili; Hossein Mortazavi; Sheyda Chams-Davatchi; Maryam Daneshpazhoooh; Maede Rayati Damavandi; Zeinab Aryanian; Ali Akbar Amirzargar

Volume 10, Issue 1 , Winter 2013, Pages 1-9

  Background: A common Human Leukocyte Antigen (HLA) class II allele, DQβ1*03:01, seems to be associated with Bullous pemphigoid (BP) in Caucasians whereas previous studies in other ethnic groups showed other HLA class II alleles as genetic predisposing factors for BP. Objective: To investigate the ...  Read More

Original Article
2. Sclareol Reduces CD4+ CD25+ FoxP3+ T-reg Cells in a Breast Cancer Model in Vivo

Shokoofe Noori; Zuhair Mohammad Hassan; Omid Salehian

Volume 10, Issue 1 , Winter 2013, Pages 10-21

  Background: Sclareol is a phytochemical used in people's diet in Southeast Asia. Objective: To investigate the immunotherapeutic effectiveness of Sclareol against breast cancer by direct intraperitoneal injection. Methods: Sclareol was isolated and purified from Salvia sclarea. Effect of Sclareol on ...  Read More

Original Article
3. Concomitant Increase of OX40 and FOXP3 Transcripts in Peripheral Blood of Patients with Breast Cancer

Maryam Hamidinia; Mehri Ghafourian Boroujernia; Abdolhassan Talaiezadeh; Ghasem Solgi; Maryam Taghdiri; Ali Khodadadi

Volume 10, Issue 1 , Winter 2013, Pages 22-30

  Background: Regulatory T cells (T-regs) have an important role in cancer by suppression of protective antitumor immune responses. Regulatory T cells express the forkhead/winged helix transcription factor (FOXP3) and OX40 molecules which have important regulatory roles in the immune system. Objective: ...  Read More

Original Article
4. Effect of Thermal Stress on MICA/B Induction in a Human Liposarcoma Cell Line

Shirin Farjadian; Shahrzad Rahimifar; Nasrollah Erfani; Ramin Lotfi

Volume 10, Issue 1 , Winter 2013, Pages 31-39

  Background: A possible mechanism by which hyperthermia enhances tumor immunogenicity is the induction of NKG2D ligands on tumor cells. Although the expression of MHC class I chain-related protein A and B (MICA/B) has previously been reported in different carcinomas, there is no information about MICA/B ...  Read More

Original Article
5. Differential Expression of CXCL1, CXCL9 CXCL10 and CXCL12 Chemokines in Alopecia Areata

Nahid Zainodini; Gholamhossein Hassanshahi; Mohammad Kazemi Arababadi; Hossein Khorramdelazad; Afshin Mirzaei

Volume 10, Issue 1 , Winter 2013, Pages 40-46

  Background: Alopecia Areata (AA) is a non-scarring, autoimmune disorder which causes hair loss. Inflammatory reactions are involved in hair loss of the scalp and/or body. The involvement of chemokine receptors in the pathogenesis of AA is well defined among which, CXCL1 acts on neutrophils and CXCL9, ...  Read More

Original Article
6. Increased IL-17A but Decreased IL-27 Serum Levels in Patients with Multiple Sclerosis

Zohreh Babaloo; Reza Khajir Yeganeh; Mehdi Farhoodi; Behzad Baradaran; Mohamadreza Bonyadi; Leila Aghebati

Volume 10, Issue 1 , Winter 2013, Pages 47-54

  Background: Effector CD4+ T cell subsets play an important role in Multiple Sclerosis (MS). Interleukin-27 (IL-27) suppresses Th (Th1, Th2 and Th17) cells and dampens autoimmunity and tissue inflammation by promoting the generation of Type 1 regulatory T cells (Tr1). Objective: To identify the relative ...  Read More

Original Article
7. Selective Antibody Deficiency and its Relation to the IgG2 and IgG3 Subclass Titers in Recurrent Respiratory Infections

Roya Sherkat; Parisa Shoaei; Nima Pavaneh; Anahita Babak; Nazila Kassaian

Volume 10, Issue 1 , Winter 2013, Pages 55-60

  Background: Selective antibody deficiency with normal immunoglobulins (SADNI) may be identified as part of distinct primary or secondary immunodeficiency disorders. The clinical manifestations include recurrent, often severe or prolonged, upper or lower respiratory tract infections. Objectives: To evaluate ...  Read More