Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. Construction and Expression of Hepatitis B Surface Antigen Escape Variants within the "a" Determinant by Site Directed Mutagenesis

Forough Golsaz Shirazi; Mohammad Mehdi Amiri; Hamed Mohammadi; Ali Ahmad Bayat; Azam Roohi; Jalal Khoshnoodi; Amir Hassan Zarnani; Mahmood Jeddi-Tehrani; Gholam Ali Kardar; Fazel Shokri

Volume 10, Issue 3 , Summer 2013, Pages 127-138

  Background: The antibody response to hepatitis B surface antigen (HBsAg) controls hepatitis B virus infection. The "a" determinant of HBsAg is the most important target for protective antibody response, diagnosis and immunoprophylaxis. Mutations in this area may induce immune escape mutants and affect ...  Read More

Original Article
2. Arteether Exerts Antitumor Activity and Reduces CD4+CD25+FOXP3+ T-reg Cells in Vivo

Maryam Azimi Mohamadabadi; Zuhair Mohammad Hassan; Ahmad Zavaran Hosseini; Mehrdad Gholamzad; Shekoofe Noori; Mehdi Mahdavi; Hamidreza Maroof

Volume 10, Issue 3 , Summer 2013, Pages 139-149

  Background: Chemo-immunotherapy is one of the new achievements for treatment of cancer, by which the success of anti-cancer therapy can be increased. In vitro studies have been shown that Arteether (ARE) induces apoptosis in tumor cells, but not in normal cells. Objective: To investigate the cytotoxic ...  Read More

Original Article
3. KIR Gene Content Does Not Contribute to Susceptibility to Graves’ Disease

Elham Ashouri; Mohammad Hossein Dabbaghmanesh; Amirhossein Hadaegh; Soodeh Rowhanirad; Marizeh Bakhshayeshkaram; Gholamhossein Ranjbar Omrani

Volume 10, Issue 3 , Summer 2013, Pages 150-157

  Background: Killer cell immunoglobulin-like receptors (KIR) are expressed on NK cells and a subset of T cells. The variable KIR receptors along with their ligands, HLA class I, influence risk for autoimmune and malignant diseases. Objective: To investigate the KIR gene profiles in relation to susceptibility ...  Read More

Original Article
4. Interleukin-8 but Not Interleukin-6 Variant May Affect Susceptibility to Brucellosis

Sadaf Asaei; Manoochehr Rasouli; Ali Moravej

Volume 10, Issue 3 , Summer 2013, Pages 158-166

  Background: Increased levels of interleukin-8 (IL-8) and interleukin-6 (IL-6) in acute human brucellosis have been reported. Previous studies have shown that the production and level of IL-6 and IL-8 cytokines are associated with the polymorphism of the encoding genes. Objective: To investigate the probable ...  Read More

Original Article
5. Serum IL-18 and hsCRP Correlate with Insulin Resistance without Effect of Calcitriol Treatment on Type 2 Diabetes

Marzieh Akbarzadeh; Mohammad Hassan Eftekhari; Mohammad Hossein Dabbaghmanesh; Jafar Hasanzadeh; Marzieh Bakhshayeshkaram

Volume 10, Issue 3 , Summer 2013, Pages 167-176

  Background: Chronic low-grade systemic inflammation presented in Type 2 diabetes mellitus plays a major role in disease progression as well as development of micro- and macro-vascular complications of diabetes. Therefore, reducing inflammation can be beneficial in prevention of diabetes complications. ...  Read More

Original Article
6. Interleukin-17 Gene Expression and Serum Levels in Children with Severe Asthma

Soheila Alyasin; Mohammad Hossein Karimi; Reza Amin; Maryam Babaei; Sepideh Darougar

Volume 10, Issue 3 , Summer 2013, Pages 177-185

  Background: IL-17 is a major cytokine player in T cell mediated leukocyte associated inflammation. IL-17 is also recognized to participate in the pathophysiology of asthma. Objective: To determine the role of IL-17 in predicting severe asthma. Methods: We obtained serum samples from asthmatic children ...  Read More