Volume 18 (2021)
Volume 17 (2020)
Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. Detection of IL-20R1 and IL-20R2 mRNA in C57BL/6 Mice Astroglial Cells and Brain Cortex Following LPS Stimulation

Bahareh Abd Nikfarjam; Massoumeh Ebtekar; Farzaneh Sabouni; Zahra Pourpak; Maryam Kheirandish

Volume 10, Issue 2 , Spring 2013, Pages 62-69

  Background: Astrocytes, which comprise ~90% of overall brain mass, are involved in brain immunity. These cells represent the non-professional class of CNS-resident APCs and may promote or inhibit CNS inflammation depending on the cytokines they secrete. IL-10 family of cytokines and their receptors, ...  Read More

Original Article
2. Long Acting Propranolol and HSP-70 Rich Tumor Lysate Reduce Tumor Growth and Enhance Immune Response against Fibrosarcoma in Balb/c Mice

Ahmad Khalili; Zuhair Muhammad Hassan; Shahram Shahabi; Ali Akbar Pourfathollah; Seyed Nasser Ostad; Shokoofe Noori; Mehdi Mahdavi; Habib Haybar; Ladan Langroudi

Volume 10, Issue 2 , Spring 2013, Pages 70-82

  Background: Noradrenaline (NA), the principal neurotransmitter released from sympathetic nerve terminals, influences T-cell maturation, not only directly in developing T cells, but also indirectly, by acting on the thymic nonlymphoid cells. In vitro and in vivo studies have demonstrated the anti-proliferative, ...  Read More

Original Article
3. Interleukin-17 Serum Levels and TLR4 Polymorphisms in Ulcerative Colitis

Mojgan Mohammadi; Mohammad Javad Zahedi; Amin Reza Nikpoor; Mohammad Reza Baneshi; Mohammad Mahdi Hayatbakhsh

Volume 10, Issue 2 , Spring 2013, Pages 83-92

  Background: Inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including Crohn’s disease and ulcerative colitis (UC). IL-17 has been the target of intensive research in autoimmune diseases. The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 ...  Read More

Original Article
4. Hyperthermia Increases Natural Killer Cell Cytotoxicity against SW-872 Liposarcoma Cell Line

Shirin Farjadian; Marzie Norouzian; Vahid Younesi; Azin Ebrahimpour; Ramin Lotfi

Volume 10, Issue 2 , Spring 2013, Pages 93-102

  Background: Although there is convincing data in support of the effectiveness of hyperthermia in tumor therapy, the molecular mechanisms underlying the clinical effects of hyperthermia are still poorly understood. Objective: To investigate natural killer (NK) cell cytotoxicity against heat-treated SW-872 ...  Read More

Original Article
5. MiR-143 Induces Expression of AIM2 and ASC in Jurkat Cell Line

Mohammad Momeni; Mohammad Reza Mirzaei; Nahid Zainodini; Gholamhossein Hassanshahi; Mohammad Kazemi Arababadi

Volume 10, Issue 2 , Spring 2013, Pages 103-109

  Background: Absent in Melanoma 2 (AIM2) is an intracellular microbial dsDNA sensor which plays an important role in production of proinflammatory cytokines through Apoptosis associated Speck-like protein containing a Caspase activation and recruitment domain (ASC) and Caspase-1. Micro-RNAs (miRNAs) play ...  Read More

Original Article
6. Immunogenicity of a New Recombinant IpaC from Shigella dysenteriae Type I in Guinea Pig as a Vaccine Candidate

Fatemeh Malaei; Mahdi Hesaraki; Mojtaba Saadati; Ali Mohammad Ahdi; Mohammad Sadraeian; Hussein Honari; Shahram Nazarian

Volume 10, Issue 2 , Spring 2013, Pages 110-117

  Background: Recombinant vaccine technology is one of the most developed means in controlling infectious diseases. However, an effective vaccine against Shigella is still missing. Objective: To evaluate recombinant IpaC protein of Shigella as a vaccine candidate. Methods: In this study we cloned IpaC ...  Read More

Original Article
7. Immune Deviation in Recurrent Vulvovaginal Candidiasis: Correlation with Iron Deficiency Anemia

Nadereh Naderi; Zahra Etaati; Mansoreh Rezvani Joibari; Seyed Alireza Sobhani; Said Hosseni Tashnizi

Volume 10, Issue 2 , Spring 2013, Pages 118-126

  Background: Iron Deficiency Anemia (IDA) has been controversially linked to IL-4 production in previous studies. A predominant Th1 response leads to resistance against recurrent vulvovaginal candidiasis (RVVC), whereas a Th2 response exacerbates the disease. Objective: To investigate the possible effect ...  Read More