Volume 16 (2019)
Volume 15 (2018)
Volume 14 (2017)
Volume 13 (2016)
Volume 12 (2015)
Volume 11 (2014)
Volume 10 (2013)
Volume 9 (2012)
Volume 8 (2011)
Volume 7 (2010)
Volume 6 (2009)
Volume 5 (2008)
Volume 4 (2007)
Volume 3 (2006)
Volume 2 (2005)
Volume 1 (2004)
Original Article
1. Effects of Long-time Exposure to Lipopolysaccharide on Intestinal Lymph Node Immune Cells and Antibodies Level in Mice

Chao Li; Dexue Ma; Mingming Zhang; Liyan An; Chenchen Wu; Hongchao Zhou

Volume 17, Issue 3 , Summer 2020, Pages 175-184


  Background: Endotoxin, widely present in the living environment of humans and animals, leads to endotoxemia during a short period. However, the long-term effects of endotoxin on immune function are unclear. Objective: To determine the importance of long-term endotoxin treatment on function of immune ...  Read More

Original Article
2. IL-6 and IL-10 Closely Correlate with Bacterial Bloodstream Infection

Jingjing Guan; Zhongyong Wang; Xiaoyuan Liu; Yujie Jiang; Qiuqi Gao; Qing Wu; Hong Lu; Lianfeng Wu; Zhuo Zhang; Xiangyang Lin; Jingjing Qian

Volume 17, Issue 3 , Summer 2020, Pages 185-203


  Background: Given the high mortality of bacterial bloodstream infections (BSI), blood culture results do not meet clinical needs timely due to being time-consuming and having low positive rate. Whether we can identify the severity and type of bacterial infections by cytokines is a controversial issue. ...  Read More

Original Article
3. Variants in Intron 4 of PD-1 Gene are Associated with the Susceptibility to SLE in an Iranian Population

Yousef Khanjari; Morteza Oladnabi; Nafiseh Abdollahi; Ahmad Heidari; Saeed Mohammadi; Alijan Tabarraei

Volume 17, Issue 3 , Summer 2020, Pages 204-214


  Background: Programmed cell death protein 1 (PD-1) is a negative costimulatory molecule with immunomodulatory properties. Recently, PD-1 gene defects have attracted attention in the pathogenesis of SLE. Objective: Here, we assessed the association of PD-1 gene polymorphisms in intron 4 and haplotypes ...  Read More

Original Article
4. Association of rs11558471 in SLC30A8 Gene with Interleukin 17 Serum Levels and Insulin Resistance in Iranian Patients with Type 2 Diabetes

Mehran Ahmadi; Abdolkarim Mahrooz; Saeid Abediankenari; Nasim Hayati Roodbari

Volume 17, Issue 3 , Summer 2020, Pages 215-225


  Background: Functional single nucleotide polymorphisms in zinc transporter 8 (ZnT8) gene may be key determinants of humoral autoreactivity to ZnT8. Objective: The present study is expected to provide new information on the association of rs11558471 in ZnT8 gene with IL-17 levels and insulin resistance ...  Read More

Original Article
5. Hereditary Angioedema Due to C1-Inhibitor Deficiency in Romania: First National Study, Diagnostic and Treatment Challenges

Gabriella Gabos; Valentin Nadasan; Eniko Mihaly; Daniela Dobru

Volume 17, Issue 3 , Summer 2020, Pages 226-235


  Background: Hereditary angioedema (HAE) is a rare genetic potentially life-threatening disease characterized by episodic non-pruritic subcutaneous and submucosal edema attacks in different parts of the body. Objective: To assess the status of Romanian HAE patients after the recent introduction of a new ...  Read More

Short Paper
6. Importance of MMP-8 in Salivary and Gingival Crevicular Fluids of Periodontitis Patients

Kazem Fatemi; Seyed Abdolrahim Rezaee; Seyed Ali Banihashemrad; Sanaz Keyvanfar; Meghdad Eslami

Volume 17, Issue 3 , Summer 2020, Pages 236-243


  Background: Matrix metalloproteinases (MMPs) stimulate alveolar bone loss in chronic periodontitis. Objective: To evaluate the salivary and gingival crevicular fluid (GCF) levels of MMP-8 in patients with moderate to severe chronic periodontitis. Methods: 42 participants were divided into two groups: ...  Read More

Case Report
7. A Patient with CTLA-4 Haploinsufficiency with Multiple Autoimmune Presentations: A Case Report

Fatemeh Zaremehrjardi; Leila Baniadam; Farhad Seif; Saba Arshi; Mohamad Hasan Bemanian; Sima Shokri; Afshin Rezaeifar; Morteza Fallahpour; Mohammad Nabavi

Volume 17, Issue 3 , Summer 2020, Pages 244-249


  Increased susceptibility to autoimmunity, malignancy, and allergy in addition to recurrent infections are the main characteristics suggesting for the primary immunodeficiency diseases (PID). CTLA-4 is predominantly expressed on activated and regulatory T-cells, which can bind to CD80/CD86 molecules on ...  Read More

Case Report
8. Plasmodium Vivax Malaria: Usual Illness with Dysregulated Immune Profile

Richa Gupta; Sonali Dixit; Neha Garg; Mrinalini Kotru

Volume 17, Issue 3 , Summer 2020, Pages 250-254


  Afebrile Plasmodium vivax disease is believed to be extremely rare; and so is the association of a secondary immune thrombocytopenia due to Plasmodiun vivax malaria. This is a case of malaria presenting in an atypical manner. A middle aged male (31 years) came with occasional bleeding around gums, small ...  Read More